OCT revealed anatomical evidence of loss of ganglion cell layers, causing marked thinning of the macula and parafoveal region. Decreased parafoveal retinal thickness and volume measurements are an evidence of chloroquine toxicity, due to an accumulation of lipofuscine.
Bellios, Nikolaus, Dr.med., Augenklinik, Friedrich-Alexander-Universität Erlangen-Nürnberg¦5, Erlangen, Deutschland