Rod and Cone Photoreceptor Degeneration Associated With Long-term Chloroquine Use (OCT)
Rod and Cone Photoreceptor Degeneration Associated With Long-term Chloroquine Use (OCT)
52 years of age, male, BCVA RA cc 0.1, LA cc 0.1.
OCT:
Inside the perifoveal ophthalmoscopic pigmentary changes Spectral OCT revealed an impairment of outer nuclear layer, external limoting membrane, junction of the inner and outer photoreceptor segment layers (IS/OS), and retinal pigment epithelium layer. In this area SD-OCT images demonstrated loss of photoreceptor inner segment/outer segment (IS/OS) junction and a downward displacement of inner retinal structures.
Outside the perifoveal ophthalmoscopic pigmentary changes SD-OCT images demonstrated only a weak impairment of outer nuclear layer, external limoting membrane, and junction of the inner and outer photoreceptor segment layers (IS/OS).
Michelson, Georg, Prof. Dr. med., Interdisziplinäres Zentrum für augenheilkundliche Präventivmedizin und Imaging, Augenklinik, Friedrich-Alexander Universität Erlangen, Erlangen, Germany