Atlas of Ophthalmology

Female, age of 16 years, BCVA RA 1.0, LA 0.5, amblyopia at LA. We report clinical findings in a case of a 16-year-old girl with unilateral extensive hyperplastic persistent pupillary membrane. Due to amblyopia no surgery was recommended. Persistent pupillary membrane is a congenital, incomplete involution of the tunica vasculosa lentis. These membranes are usually tenacious, with fine fibrils attached to the iris collarette on one side, with the other end either free floating or attached to the lens or iris focally on the opposite side. This condition represent ectopic iris tissue on the lens with abnormal iris stroma caused by aberrant involutional changes in the primitive embryological vascular system of anterior segment. Dense and thick membranes, particularly within the pupil, may result in deprivation amblyopia. Extensive hyperplastic persistent pupillary membrane can surgically removed without injury to the crystalline lens (1). Literature (1) Ramappa M, Murthy SI, Chaurasia S, Singhla R, Rathi VM, Vemuganti GK, Sangwan VS. Lens-preserving excision of congenital hyperplastic pupillary membranes with clinicopathological correlation.J AAPOS. 2012 Apr;16(2):201-3.

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